Zytorvi

What is Zytorvi?

Zytorvi, our brand name for Toripalimab, is a monoclonal antibody used in cancer treatment, specifically targeting the PD-1 protein on immune cells. It is approved for treating nasopharyngeal carcinoma, both as a first line treatment in combination with chemotherapy and as a single agent in advanced cases.

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Presentation

Storage Conditions

2-8 degrees Celsius (refrigerate), Do not freeze.

Presentation

Vial containing solution for infusion

Route of Administration

Intravenous (IV) (upon prescription only and administered by a healthcare provider)

Indications

Nasopharyngeal Carcinoma (NPC):

NPC is a type of cancer that originates in the nasopharynx, the upper part of the throat behind the nose. It is often associated with Epstein-Barr virus (EBV) infection. Treatment typically involves a combination of chemotherapy, radiation therapy, and immunotherapy.

How Toripalimab works?

Mechanism of Action

Toripalimab is a humanized monoclonal antibody that targets PD-1, a checkpoint protein on T cells that normally helps keep the body's immune responses in check. By blocking PD-1, Toripalimab enhances the immune system's ability to attack cancer cells. This mechanism involves the inhibition of the PD-1/PD-L1 pathway, which is crucial for the immune evasion of cancer cells.