Womab

What is Womab?

Womab (pertuzumab) is a monoclonal antibody used in the treatment of HER2-positive breast cancer, including metastatic breast cancer and early breast cancer. It works in combination with trastuzumab and chemotherapy.

Storage Conditions

2-8 degrees Celsius (refrigerate), Do not freeze

Presentation

Vial containing concentrate for solution for infusion

Route of Administration

Intravenous (IV)(upon prescription only and administered by a healthcare provider.)

Indications

HER2-Positive Metastatic Breast Cancer (mBC):

mBC is an advanced stage of breast cancer where the disease has spread beyond the breast to other parts of the body, requiring systemic treatments to manage progression and symptoms.

How Pertuzumab works?

Mechanism of Action

Pertuzumab binds to the HER2 receptor, a key driver of cell growth and differentiation in HER2-positive cancers. By inhibiting the dimerization of HER2 with other HER receptors, pertuzumab prevents the activation of downstream signaling pathways that promote tumor cell proliferation and survival. This mechanism helps to inhibit tumor growth and improve patient outcomes.